Type of Document Master's Thesis Author Daniel, Johnni Hutcherson Author's Email Address bez2@cdc.gov URN etd-07302007-144955 Title ANALYZING LIMITATIONS IN EXPOSURE ESTIMATES BASED ON SELF-REPORTED DIETARY INTAKE OF CAFFEINATED BEVERAGES IN THE BALTIMORE-WASHINGTON INFANT STUDY, 1981-1989. Degree MPH Department Public Health Advisory Committee
Advisor Name Title Derek Shendell Committee Chair Adolfo Correa Committee Member Ike Okosun Committee Member Jan Cragan Committee Member Keywords
- pregnancy
- congenital heart defects
- cardiovascular malformations
- caffeine consumption
Date of Defense 2007-06-07 Availability restricted Abstract Caffeine, a mild central nervous system stimulant, is a natural component of common hot and cold beverages like coffee, tea, sodas and cocoa. Animal studies have demonstrated caffeine’s teratogenic effects when administered at high concentrations; however, epidemiologic studies have yielded inconsistent results in humans. Because caffeine containing beverages are commonly consumed by pregnant women, we examined the prevalence of use and explored possible associations of maternal caffeine consumption with cardiovascular malformations in 3,274 cases matched with 3,519 controls enrolled in the 1981-89 “Baltimore-Washington Infant Study,” a population-based case-control investigation. We explored several key aspects of the quality of and distribution of measurements of caffeine consumption among mothers in the study population. We concluded with recommendations for refining data collection to reduce potential bias associated with assessing both caffeine content and changes in caffeine consumption during pregnancy in order to inform future research studies and birth defects/adverse birth outcomes surveillance programs.Files
Filename Size Approximate Download Time (Hours:Minutes:Seconds)
28.8 Modem 56K Modem ISDN (64 Kb) ISDN (128 Kb) Higher-speed Access Daniel_Johnni_H_2007Summer_MPH.pdf 904.94 Kb 00:04:11 00:02:09 00:01:53 00:00:56 00:00:04 indicates that a file or directory is accessible from the Georgia State University campus network only.